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CFTR InPlex™

Catalog Number: 95-424

The Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) InPlex™ reagents* detect the following mutations located in the CFTR gene (q7p31.2):

E60X	Q493X	G551D	R1162X	3120+1 G>A
G85E	ΔI507	R553X	D1270N	3659delC
R117H	ΔF508	R560T	W1282X	3849+10kbC>T
Y122X	F508C	621+1 G>T	N1303K	3849+4 A>G
I148T	V520F	711+1 G>T	1717-1 G>A	3876delA
R334W	G542X	1078delT	1898+1 G>A	3905insT
R347P	S549N	Y1092X C>A	2183AA>G	IVS8-5T
R347H	S549R A>C	Y1092X C>G	2184delA	IVS8-7T
394delTT	S549R T>G	D1152H	2789+5 G>A	IVS8-9T
A455E

Requires an instrument that can detect fluorescence of FAM and Redmond Red dyes such as a Tecan^® GENios^®, GENios^® FL or Infinite^® fluorometer.

*Analyte Specific Reagent. Analytical and performance characteristics are not established.

The Invader^® chemistry is protected by foreign and domestic patents.